Particularities of the association of systemic arterial hypertension at patients with sleep apnea syndrome
Stefan Mihaicuta1, Sorin Ursoniu2, Daniel Lighezan3, Danina Muntean4, Ovidiu Fira-Mladinescu4, Raul Horhat5, Stefan Frent1, Dan Gaita3, Voicu Tudorache1
1Clinica de Pneumologie, UMF V. Babes Timisoara
2 Departamentul de Sanatate Publica, UMF V. Babes Timisoara
3 Clinica de Cardiologie, UMF V. Babes Timisoara
4 Departamentul de Fiziopatologie, UMF V. Babes Timisoara
5 Informatica Medicala, UMF V. Babes, Timisoara
Abstract
Aim. Analysis of the association between sleep apnea syndrom (SAS) and sistemic hypertension (SHT) at consecutive patients with suspicion of SAS.
Method. We included 427 consecutive patients evaluated for SAS at Babes University Sleep Lab, Timisoara (March 2001- March 2007), medical history, anthropometric measurements, cardiovascular evaluation, inclusion/exclusion criteria, Epworth scale, polisomnography, statistical analysis with STATA 9.2.
Results. Systemic hypertension (SHT9 at 245 (58,05%) of patients, pre- SHT at 11,37%, stage I 11,37%, stage II 29,14%, stage III 6,16%, onset of disease 7,26 ± 6,13 years. Diferences between groups without and with SHT: apnea-hypopnea index (AHI) 27,71±27,94/h, CI 23,55-31,78 vs 38,6 ± 26,16/h, CI 35,34-41,85, p < 0,001, body mass index (BMI) 31,43 ±6,26 kg/m2, CI 30,50 - 32,36 vs 34,21 ± 6,11 kg/m2, CI 33,45- 34,97 p < 0,001, desatution index 20, 21 ± 26,35/h, CI 16,28 - 24,13 vs 31,12 ± 29,16 CI 27,49-34,75, p < 0,001, medium desaturation 92, 93 ± 5,03%, CI 92,18- 93,68 vs. 90,6 ± 8,42, CI 89,55 - 91, 64, p < 0,001, medium age 47,66 ±12,57 years, CI 45,79 - 49,52 vs. 55, 06 ±10,35 years, CI 53,77 -56,35, p = 0,0047, abdominal circumference 117,77 ±15, 44 cm, CI 115,48 - 120, 06 vs. 121,68 ±14, 66 cm, CI 119,85 - 123, 51, p = 0,0082, neck circumferance 42,98 ± 4,84 cm, CI 42,26- 43,70 vs. 44,.24 ± 4.59 cm, CI 43,67 - 44,81 p = 0,0068, Epworth score 9,09 ± 4,81, CI 8,37- 9,80 vs. 10,77 ± 5,19, CI 10, 12 - 11,42, p = 0,007.
Conclusion. SHT represents the most frecquent pathological association at SAS patients. Diferences between groups without and with SHT were statistical significant in apnea - hypopnea index, body mass index, desaturation index, medium desaturation, age, abdominal circumference, neck circumference, Epworth score.
Contact : mihaicuta@yahoo.com
