Non invasive ventilation in acute hypercapnic exacerbations of COPD

Abstract

Elena Cristina Mitrofan¹, Andreea Steciuc², Gianina Rusu¹

¹Universitatea de Medicina si Farmacie "Gr. T. Popa", Iasi

²Spitalul Clinic de Pneumologie, Iasi

Contact: Elena Cristina Mitrofan, criselend@yahoo.com,

Spitalul Clinic de Pneumologie Iasi, Strada Dr. I. Cihac, nr. 30, Iasi

ABSTRACT

Bed limitations and financial constraints can affect patients admission with acute hypercapnic decompensation of COPD in critical care setting. The goal of our study was to evaluate non invasive ventilation efficiency performed outside ICU and to compare our result with those from published studies. Method: 49 patients with well known COPD were ventilated by VPAP^TM III ST-A, ResMed. Results: With a mean age of 72,1 years and male predominance, we obtained a rate of success of 85,72% with a mean time of ventilation of 63,63 ± 26,04 hours. The risk of failure was 5 times much greater for the patients with pH ≤ 7,25, the predictive positive value was of 83,3%. Conclusion:

This study proved the value of non invasive positive pressure ventilation in hypercapnic exacerbation of COPD with improved in acidosis, hypercapnia, and altered level of consciousness. The result of our study are similar with those from published literature.

Key words: non invasive ventilation, COPD, respiratory acidosis, cor pulmonale

Non-invasive positive pressure ventilation in COPD exacerbations