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CLINICAL CASES

Infecţia cu Mycobacterium simiae la o femeie imunocompetentă

Seyyed Hamid Hashemi, Maria Shirvani, Pershang Nazemi
Infecţia cu Mycobacterium simiae la o femeie imunocompetentă
Mycobacterium simiae is an uncommon cause of pneumonia in immunocompromised host. We report a case of pulmonary infection due to M. simiae in animmunocompetent old woman who suffered from chronic cough. Based on positive sputum smear for acidfast bacilli, the disease was diagnosed as tuberculosis. Failure of response to antituberculous drugs resulted in further evaluation and the identification of M. simiae by molecular method on sputum culture. M. simiae should be considered as a potential cause of lung disease in patients suspected to have tuberculosis but failed to respond to antituberculosis therapy.

Infecţia cu Mycobacterium simiae la o femeie imunocompetentă

The impact of cystic fibrosis upon the evolution of pregnancy, fetus and newborn

Svetlana Șciuca, Ștefan Gaţcan, Irina Castraveț, Viorica Fuior, Serghei Covanțev, Ludmila Balanetchi, Selevestru Rodica
The impact of cystic fibrosis upon the evolution of pregnancy, fetus and newborn
International statistics confirm that in recent years more and more women with cystic fibrosis report pregnancy. In the past, pregnancy was associated with a high rate of miscarriage, premature birth, and newborn mortality. We report a case of a 22-year-old female with cystic fibrosis who got pregnant being in an advanced stage of the disease, associating COPD, bilateral saccular bronchiectasis, multiple air cysts of the right upper lobe, pulmonary fibrosis, chronic pulmonary infection with Pseudomonas aeruginosa, Burkholderia cepacia, second-degree chronic respiratory failure, exocrine pancreatic insufficiency associated with severe weight and height growth disorders (body weight: 43 kg, height: 158 cm, BMI: 17.22). At the term of 35 weeks of gestation the patient underwent the planned caesarean section, giving birth to a live newborn male with a body mass of 1470 g, height: 40 cm, head circumference: 29 cm, thoracic circumference: 23 cm, Apgar score: 7/8. The pregnancy in this patient with a severe form of stic fibrosis, chronic pulmonary destructive changes, severe height and weight deficiencies was carried on with complications and negative impact upon the child with chronic intrauterine hypoxia, intrauterine growth retardation, highly marked morphological and functional immaturity.