General reviwes

ABSTRACT

Traditional medical care considers symptomatic and objective findings of disease as the main outcome measure. However, modern medical practice defines health as a complete state of well being including physical state and patient's perception of social and psychological well being. Therefore, the main aim of therapeutic management needs to be "the control of disease related and unrelated to the health condition of the individual in terms of functional and emotional well being". This necessitates evaluation of control status in cases with cystic fibrosis via evaluation of symptomatic and physical findings with laboratory techniques and psycho-somatic instruments. The aim of this review article is to define the three main indicators of control and to provide initial ideas for development of a new instrument that covers all.

Keywords: cystic fibrosis, control concept, patient reported outcome measures

ABSTRACT

The first case of endobronchial sarcoidosis was described by Benedict and Castelman in 1941. The endoscopic aspects in sarcoidosis can reveal: erythema, edema, network of capillary ectases, granularity, irregular mucosa thickening, macro and micro nodules in mucosa, bronchial and tracheal stenosis, distortions, tractions (including at the large and medium airways), sometimes bronchial ectases secondary to these modifications. The doctors must be aware of the possibility of affecting the great airways in sarcoidosis, such situation, although rare, could make for a difficult diagnosis, especially in the case of the tusigen syndrome or persistent and unexplained wheezing. The more the parenchimal disease progresses, the greater is the frequency of the airways being affected.

Keywords: bronchoscopy, airways, sarcoidosis

ABSTRACT

Complications and disability after radical therapy for lung cancer can be predicted by preoperative functional evaluation. Functional tests and threshold values of the parameters have been described and included in a well-validated algorithm, ensuring functional reserve evaluation of candidates for pulmonary resection. There are no defined tests or cut-off values to provide predictions of complications after chemo-radiotherapy or limited pulmonary resections.

Keywords: lung resection, functional evaluation, algorithm, predicted post-operative